His labors were apostolic and tireless. For 47 years Andrews pastored churches in the northeastern United States. He developed a preaching circuit that took him across the border into Quebec, Canada, where he was instrumental in helping to plant the first Baptist Church (Particular) on French-Canadian soil. Elisha was as comfortable baptizing new converts in icy Canadian waters as he was preaching from his New England pulpit. He was an apologist, a missionary, a prolific writer, and an evangelist who experienced genuine revival. His ministry was filled with preaching Christ in His fullness and countering the errors of Arminianism and pedo-baptism. His views on the American Revolution were vastly different from many ministers of his day and certainly worth reading.